MANIC DEPRESSIVE ILLNESS

Genetics of manic depressive illness.

Manic depressive illness is a common and frequently debilitating familial psychiatric disorder. Efforts to understand the mechanisms of inheritance have been hindered by the complexity of the phenotype, which may range from benign mood swings to chronic psychosis, and by apparently nonmendelian modes of transmission. Early reports of linkage to chromosomal loci have fallen into doubt; however t...

Multiple biochemical correlates of manic-depressive illness.

State-dependent tardive dyskinesia in manic-depressive illness.

We report the occurrence of a drug-resistant tardive dyskinesia coexistent with Parkinsonism-like symptoms in a manic-depressive patient. The tardive dyskinesia completely disappeared during the manic phases and recurred after remission over the course of different mood-cycles.

Lithium, manic-depressive illness, and psychological test performance.

Lithium, manic-depressive illness, and psychological test performance For over 10 years patients responding to treatment at a lithium clinic' have been free from psychiatric symptoms. Little is known about the psychological performance of such patients, but a report,2 using the Minnesota Multiphasic Personality Inventory (MMPI), confirmed that lithium produces a response in depression. Clinical...

The Use of Carbamazepine in Patients with Manic Depressive Illness

16 cases of affective disorder were studied. 8 patients received carbamazepine and 8 received either chlorpromazine or imipramine. Ratings were carried out on the Hamilton Rating Scale for Depression, Bech Rafaelsen Mania Rating scale and a side-effects symptom check list. Garbamazepine was found to be an effective treatment for affective disorders, possessing both anti-manic as well as anti-de...